Basophils are white blood cells that the bone marrow makes. They play a role in a healthy immune system. Levels that are higher or lower than usual may be a sign of inflammation, hyperthyroidism, or ...

Indolent systemic mastocytosis (ISM) is a type of mastocytosis in which fewer clonal mast cells accumulate, thereby slowing the disease course and offering a better prognosis than other, more ...

Inflammation is a crucial part of the body’s defense mechanism, playing a key role in fighting infections and repairing tissue damage. Basophils, a type of immune cell that makes up less than 1% of ...

C. Ohnmacht et al., “Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths,” Immunity, 33:364-74, 2010. Free F1000 Evaluation Basophils were deemed critical in ...

Children with peanut allergy who achieved remission with sublingual immunotherapy (SLIT) had lower basophil activation before treatment and greater suppression of basophils at 1 year than those who ...

Basophils, though the rarest granulocytes, have emerged as pivotal modulators of immune responses in both allergic inflammation and autoimmunity. These cells are now recognised for their ability to ...

Higher baseline monocyte counts, along with preserved basophils and low C-reactive protein, independently predict complete remission on anti-IgE therapy for CSU.

Basophils, a type of white blood cell, promote recovery from acute respiratory distress syndrome (ARDS) in mice, according to researchers at Science Tokyo. In a mouse model of ARDS, basophils were ...

A recent study reveals the pivotal role of tristetraprolin (TTP), an RNA-binding protein, in regulating inflammatory responses in basophils, immune cells central to allergic reactions. The research ...